Parkinson's Disease Non-motor Symptoms in Pakistani Patients

Abstract

Background: Among elderly adults in Pakistan, Parkinson's is one of the most prevalent degenerative disorders.  Although the occurrence of each non-motor symptom (NMS) in Pakistani patients is unclear, these NMS may have an effect on the health of the patients. Finding out how common these NMS are among Parkinson's patients in Pakistan is the goal of this study.

Methodology: 540 Parkinson's disease participants from all provinces in Pakistan participated in cross-sectional    research. Only the non-motor part of scale (UPDRS) was noted. After NMS assessments, the frequency and impact of gender on each symptom were discovered.

Results: Every patient stated experiencing at least one non-motor symptom. The most common symptom were    depression (80%), speech issues (80%), and balance abnormalities (86.3%). Gender differences play in the occurrence of non-motor disorders in Parkinson's.

Conclusion: NMS are prevalent and significantly affect Parkinson disease patients' activities of daily life. In Pakistani Parkinson's patients, a larger proportion of NMS is linked to advanced disease stage. NMS contribute to major severity of disease in Parkinson’s patients in Pakistani population suffering from this condition and should be given proper attention and medical care. We postulated that the existence of non-motor symptoms in Parkinson disease patients may manifest differently in various genders and that this should be further studied.